24 2021 ESG Report Introduction Climate change Appendices Transparency Healthy workforce and communities Responsible supply chain Product impact 2030 goals: 1 2 3 4 We will commit to setting science-based emissions reduction targets across all scopes, in line with 1.5°C emissions scenarios and the criteria and recommendations of the Science Based Targets initiative. Reduce Scope 1 and 2 emissions by 46% by 2030 (from 2019 baseline, absolute). Be carbon-neutral across direct operations by 2040. Scope 3 emissions targets for material Scope 3 categories expected to be set within 2 years. We will advocate for net-zero emissions. We will achieve additional environmental efficiency targets in our direct operations. We will use our capabilities to contribute to solutions that address unmet climate-related health needs. Our commitment: Minimize our contribution to global emissions and utilize our capabilities to address unmet health needs for climate- vulnerable populations Metrics and targets 2030+ impact area: climate change BD commitment and goals 9 Market-based approach quantifies Scope 2 GHG emissions based on GHG emissions emitted by the generators from which the reporter contractually purchases electricity bundled with contractual instruments, or by instruments on their own (e.g., utility-specific emission factors, renewable energy certificates). Climate change management Details of how we manage governance, strategy, and risks and opportunities can be found in the TCFD section of the appendices . 2030+ goals: Reduce Scope 1 and 2 by 46% by 2030 (from 2019 baseline, absolute) Be carbon-neutral across direct operations by 2040 Scope 3 emissions targets for material Scope 3 categories to be set within 2 years Current status: Decreased by 7%—(market-based 9 , excluding unbundled REC purchase in FY 2019), increased by 23%—(market-based, including unbundled REC purchase in FY 2019). Baselines established for category 1, 4 and 9. Project initiated to calculate baseline for category 11 and 12.