OUR PURPOSE PIONEERING SCIENCE 119 ABOUT THIS REPORT BIOGEN 2021 YEAR IN REVIEW PATIENTS OUR PEOPLE ENVIRONMENT COMMUNITY REPORTING About this report The 2021 Year in Review is based on data from calendar year 2021. In some instances, we include information on initiatives or activities that began in 2021 and continued into 2022. Unless otherwise indicated, content in the data tables below covers the period Jan. 1, 2021-Dec. 31, 2021. This report is based on the GRI Principles for Defining Report Content. Please refer to the ESG Data Table and SASB & GRI Content Indices to see which material questions and relevant indicators are reported. This also provides a view of the ways our efforts align with our support of the 17 United Nations SDGs (Global Goals), with an emphasis on those most relevant to our business, including: Data in this report cover our worldwide operations and consolidated subsidiaries but exclude joint ventures. Our operations in 2021 encompassed our major facilities in Massachusetts and North Carolina in the U.S., and in Switzerland. Our global offices and commercial fleet operations are also covered in this report. The scope of environmental data presented in this report only includes operations over which we have direct control. ERM Certification and Verification Services, Inc. (ERM CVS) assured the 2021 data for several indicators, including GHG emissions and select environmental and social indicators. See the Independent Assurance Statement for full details of the assurance scope, assurance standards used, work undertaken and conclusions, and reference the ESG Data Table for assured data (bolded 2021 data points have been assured). PURPOSE AND GOVERNANCE – Code of Business Conduct – Comprehensive Compliance Program – Corporate Governance Principles – Political Contributions Policy – Transparency Reporting – U.K. Tax Strategy – Global Tax Policy PIONEERING SCIENCE – Animal Welfare – Clinical Research and Bioethics – Clinical Trial Transparency and Data Sharing – Product Stewardship – Research Collaborations – Stem Cells – Supply Chain Responsibility – Supplier Diversity PATIENTS – Access Programs – Global Privacy Program – Patient Safety – Payments to Healthcare Professionals – Pricing Principles OUR PEOPLE – Anti-Slavery and Human Trafficking Statement – Elements of Our Culture – Environmental Health and Safety Policy – Human Rights Position Statement – Pay Equity ENVIRONMENT – Biodiversity – Climate Change Position Statement – Climate Strategy – Global Sustainability Policy Additional 2021 Disclosures – 2021 ESG Data Table – 2021 CDP Climate Change Disclosure – 2021 Annual Report – 2021 U.S. Securities and Exchange Commission Form 10-K – 2021 Independent Assurance Statement to Biogen Inc Prior disclosures – 2021 DE&I Report – 2020 Year in Review – 2019 Year in Review – 2018 Corporate Social Responsibility Report – 2017 Global Impact Report – 2016 Global Impact Report – 2015 Corporate Citizenship Report – 2014 Corporate Citizenship Report – 2013 Corporate Citizenship Report ADDITIONAL RESOURCES 2021 PRINCIPLES, POLICIES AND POSITIONS Everything we do is grounded in our Code of Business Conduct, which applies to all employees, agents and consultants acting on behalf of Biogen and its affiliates worldwide. We also are guided by a range of principles, policies and positions, including our Global Sustainability Policy and other statements on ethical business conduct, compliance, accountability and transparency, among other topics. To review the full list of our commitments, visit our Principles, Policies & Positions content on www.biogen.com, which includes the following topics: Climate Action Good Health and Well-Being Industry, Innovation and Infrastructure Responsible Consumption and Production