OUR PURPOSE PIONEERING SCIENCE 151 GRI CONTENT INDEX BIOGEN 2021 YEAR IN REVIEW PATIENTS OUR PEOPLE ENVIRONMENT COMMUNITY REPORTING GRI indicator Reporting Requirements 2021 Response Alignment SDG 416 Customer Health and Safety 416–1 Percentage of significant product and service categories for which health and safety impacts are assessed for improvement. Principles, Policies & Positions Patient Safety Environment, Product Stewardship Pioneering Science and Patients – 2021 Year in Review 416–2 a. Total number of incidents of non-compliance with regulations and/or voluntary codes concerning the health and safety impacts of products and services within the reporting period, by: • Incidents of non-compliance with regulations resulting in a fine or penalty. • Incidents of non-compliance with regulations resulting in a warning. • Incidents of non-compliance with voluntary codes. b. If the organization has not identified any non-compliance with regulations and/or voluntary codes, a brief statement of this fact is sufficient. Additional requirements for compiling: 2.1 When compiling the information specified in Disclosure 416–2, the reporting organization shall: 2.1.1 Exclude incidents of non-compliance in which the organization was determined not to be at fault. 2.1.2 Exclude incidents of non-compliance related to labeling. Incidents related to labeling are reported in Disclosure 417–2 of GRI 417: Marketing and Labeling. 2.1.3 If applicable, identify any incidents of non-compliance that relate to events in periods prior to the reporting period. Patient Safety Pioneering Science – 2021 Year in Review ESG Data Table – 2021 Year in Review 417 Marketing and Labeling 417–1 a. Whether each of the following types of information is required by the organization’s procedures for product and service information and labeling: • The sourcing of components of the product or service. • Content, particularly with regard to substances that might produce an environmental or social impact. • Safe use of the product or service. • Disposal of the product and environmental or social impacts. • Other (explain). b. Percentage of significant product or service categories covered by and assessed for compliance with such procedures. Principles, Policies & Positions Patient Safety Pioneering Science , Patients and Environment – 2021 Year in Review