BIOGEN 2021 YEAR IN REVIEW 2 OUR PURPOSE PIONEERING SCIENCE PATIENTS OUR PEOPLE ENVIRONMENT COMMUNITY REPORTING OUR PURPOSE 04 2021 highlights 05 Key awards & recognitions 06 CEO letter 11 Our purpose and business performance 12 ESG governance and strategy 13 Advancing DE&I PIONEERING SCIENCE 16 Executive summary 16 Enhancing our strategic portfolio 32 Advancing responsible product development PATIENTS 36 Executive summary 36 Advocating for patients, engaging with healthcare professionals 39 Advancing health access and equity 53 Working at the intersection of technology and well-being OUR PEOPLE 59 Executive summary 60 Fostering an ethical culture 61 Enabling employees to thrive 72 Promoting diversity, equity and inclusion ENVIRONMENT 79 Executive summary 80 Advancing Healthy Climate, Healthy Lives™ 88 Promoting environmental sustainability 94 Environmental health and safety (EHS) systems COMMUNITY 96 Executive summary 96 Engaging diverse stakeholders 98 Advancing purpose and serving humanity through corporate giving 100 20 years of serving humanity 107 10 years of Caring Deeply 110 Biogen Foundation: 2021 highlights REPORTING 115 Executive summary 115 Evolving stakeholder expectations for data disclosure 116 2021 ESG materiality assessment 119 About this report 120 ESG Data Table 128 SASB Content Index 132 GRI Content Index 153 Task Force on Climate-related Financial Disclosures Statement 15 95 78 114 58 3 35 TABLE OF CONTENTS