OUR PURPOSE PIONEERING SCIENCE 117 2021 ESG MATERIALITY ASSESSMENT BIOGEN 2021 YEAR IN REVIEW PATIENTS OUR PEOPLE ENVIRONMENT COMMUNITY REPORTING MATERIALITY MATRIX Access & Pricing Expanding the availability of affordable medicines for patients, including the world’s poor, by improving the obtainability of medicines and developing appropriate pricing models. This encompasses working with PAGs. Bioethics Addressing ethical issues emerging from advances in biology, medicine and technology, linked to public health, public policy, law, environment and well-being. Health Equity Allowing people to attain their full health potential so that no one is marginalized based on their social position or other circumstances. Information Security & Patient Privacy Adopting and implementing policies and practices that safeguard the privacy of patient information and protect data from unintended intruders. Patient Health & Outcomes Ensuring that patients are properly and effectively informed regarding medicine usage and the continuous improvement in health outcomes occurring as a result of usage. Outcomes may be measured clinically (e.g., physical examination, laboratory testing and imaging), self-reported or observed. Pharmaceuticals in the Environment Addressing types of environmental pollution from discarded pharmaceuticals, including in rivers, lakes and other bodies of water, and assessing and mitigating possible impacts and health risks. Our top ESG materiality issues Bioethics IMPORTANCE TO STAKEHOLDERS IMPACT TO BIOGEN MEDIUM HIGH Product Quality & Safety Information Security & Patient Privacy Workplace Employee Health & Safety Patient Health & Outcomes Recruitment, Talent Retention & Engagement Access & Pricing R&D, Pipeline & Innovation Pharmaceuticals in the Environment Health Equity Product Quality & Safety Pursuing high standards in product quality and safety, including management systems and auditing, that meet or exceed regulatory requirements. R&D, Pipeline & Innovation Developing innovative products that treat systemic, challenging and complex medical issues and address the unmet medical needs of patients around the globe. Recruitment, Talent Retention and Employee Engagement Attracting and retaining top talent while also finding ways to keep employees motivated and committed to the company. Workplace Employee Health & Safety Undertaking efforts to assess and mitigate potential risks that could impact the health, safety or welfare of workers and implementing activities or programs to provide employees with a safe and healthy workplace. MEDIUM HIGH Top 10 material ESG issues