OUR PURPOSE PIONEERING SCIENCE PATIENTS OUR PEOPLE ENVIRONMENT COMMUNITY REPORTING 55 WORKING AT THE INTERSECTION OF TECHNOLOGY AND WELL-BEING BIOGEN 2021 YEAR IN REVIEW developed in partnership with patients and patient groups. Elements of the experience include three simulation topics: independent living (social life), employment and education, which will be shared on social channels popular with Gen Z and millennials. Participants can explore these topics in a virtual world, while receiving tips to help patients navigate the various environments. Biogen Digital Health In April 2021, we formed Biogen Digital Health, a global unit dedicated to pioneering personalized and digital medicine in neuroscience. We believe that now, more than ever, biology and technology should go hand in hand to better meet patient needs, while enabling a shift toward more prevention-focused, affordable and equitable care. Advancing our digital health capabilities helps to enable optimization of clinical development and to improve patient outcomes – detecting diseases earlier, better measuring their progression and optimizing the patient pathway. For example, developing validated digital biomarkers may enable us to accelerate clinical development and augment the probability of success of our pipeline assets, while also creating opportunities for clinicians to better monitor disease progression through more sensitive and predictive measures than those currently available. Symptoms associated with neurological diseases and neuroplasticity also offer the hope that digital therapeutics might enable us to meet patients’ needs in new ways in the future. Advancing digital health for personalized medicine in neuroscience with TheraPanacea In December 2021, we announced a new collaboration with TheraPanacea to advance personalized digital medicine using machine learning (ML) and artificial intelligence (AI). Together, we aim to accelerate clinical development and further the understanding of the underlying pathology of neurological diseases. Our focus will be on multiple therapeutic areas in neuroscience, further building on our existing relationship. FEATURE Transforming healthcare with digital health Martin Dubuc, head of Biogen Digital Health, is among a growing number of people who believe the life sciences industry is on the cusp of a revolution – a digital shift that promises to transform patient empowerment and care. Biogen Digital Health is comprised of over 150 experts focusing on four domains: digital biomarkers, personalized healthcare, care pathway solutions and digital therapeutics. They use digital health technologies – everything from sensors and digital devices to artificial intelligence (AI) – combined with big health data to change the way neurological diseases are screened, detected, monitored and managed, ultimately enabling patients to become more active participants in their health journeys. “The way a neurological disease affects individual patients varies significantly, and this variability also applies to the way they respond to different drugs and interventions,” said Martin. “Understanding and supporting decisions based on these differences is key to improving health outcomes.” Martin noted that personalized medicine, particularly in neurology, will also depend on our ability to research and develop digital biomarkers. His team aims to do this by leveraging popular digital technologies like smartphones, sensors and wearable devices, which can provide a wide range of physiological and behavioral data signals. The team is also seeking to advance the field of digital therapeutics, where technologies are used as evidence-based medical interventions to generate biological reactions. Þ READ THE FULL ARTICLE, DIGITAL VISION: A CONVERSATION WITH MARTIN DUBUC I’ve especially grown interested in transformations in our industry related to digital and customer centricity and the promise of technology to find solutions for patients with difficult diseases.” Martin Dubuc Head of Biogen Digital Health