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The site perspective: Challenges and opportunities for support Key challenges during COVID-19 What would help IP accountability 12% 28% 27% Not enough staff and/or time 26% Not enough staff and/or time to devote to 17% studyto devote to study EDC data entry 17% 21% Reviewing my site database/chart review to Reviewing my site database/chart 17% 13% 20% find potential subjects review to find potential subjects 20% EDC query resolution 19% 19% Time for patient education about studies 22% 17% Investigator site file upkeep 22% 17% Patient phone screening and scheduling 22% 14% Pre-screening patients/referrals Pre-screening patients/referrals from outside 26% 8% from outside sources sources 7% Follow-up with current study subjects Follow-up with current study subjects to 29% 4% 2% resume their study visits to resume their study visits Monitoring visit prep 36% Additional staff to Remote Access Additional staff to Additional staff to Additional staff to conduct Technology contact new referral contact patients schedule chart/database (eSource, eReg, patients currently enrolled in appointments with Engaging and retaining patients 38% reviews to look for eMR, Telemedicine) studies current patients potential patients Major impact Minor impact Source: IQVIA US and Canada Site Survey (n=138). IQVIA Global Executive Briefing: COVID-19 June 2020; Copyright 2020 IQVIA. 16

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