AMAZON.COM,INC. PROXYSTATEMENT ANNUALMEETINGOFSHAREHOLDERS ToBeHeldonWednesday,May25,2022 Theenclosedproxyis solicited by the Board of Directors of Amazon.com, Inc. (“Amazon” or the “Company”) for the Annual MeetingofShareholderstobeheldvirtually,viatheInternet,at9:00a.m.,PacificTime,onWednesday,May25,2022,andany adjournment or postponement thereof. For more information about the Annual Meeting, including how to attend and vote your shares, please see “Annual Meeting Information” on page 104. Voting via the Internet, mobile device, or by telephone helps save money by reducing postage and proxy tabulation costs. Tovotebyanyofthesemethods,readthisProxyStatement,haveyourNoticeofInternetAvailabilityofProxyMaterials,proxy card, or voting instruction form in hand, and follow the instructions below for your preferred method of voting. Each of these voting methods is available 24 hours per day, seven days per week. Weencourageyoutocastyourvotebyoneofthefollowingmethods: VOTEBYINTERNET VOTEBYQRCODE VOTEBYTELEPHONE Shares Held of Record: Shares Held of Record: Shares Held of Record: http://www.proxyvote.com See Proxy Card 800-690-6903 Shares Held in Street Name: Shares Held in Street Name: Shares Held in Street Name: See Notice of Internet Availability or See Notice of Internet Availability or See Voting Instruction Form Voting Instruction Form Voting Instruction Form Ourprincipal offices are located at 410 Terry Avenue North, Seattle, Washington 98109. This Proxy Statement is first being madeavailable to our shareholders on or about April 14, 2022. 2022ProxyStatement 1