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GRI 102: ORGANIZATIONAL PROFILE, continued Disclosure No. Disclosure Title 2021 Response 102-10 Significant changes to the organization and its supply chain In 2021, we opened nine new IBX data centers, opened six new xScale data centers via our joint ventures, and entered three new markets resulting in an increase in our total number of data center facilities to 240, which includes the MU4 and GN1 data centers which opened in January 2022 . In September 2021, we announced that we extended Platform Equinix ® into the strategic Indian market, following the completion of the acquisition of the India operations of GPX Global Systems, Inc . In December 2021, we also announced our expansion into Africa through the planned acquisition of MainOne, a leading West African data center and connectivity solutions provider . GPX and MainOne are excluded from the reporting boundary unless noted otherwise . 102-11 Precautionary Principle or approach Equinix does not specifically apply the precautionary principle; however, Equinix complies with all applicable local, regional, federal, and international laws and regulations . We take steps to ensure that we can operate with the highest levels of integrity and reliability, and we aim to develop programs to meet or exceed industry best practices . Globally, we employ a risk-based approach to our policies and practices and seek to implement best practices around the world, including increased transparency around the impact of our operations and the policies we have in place . 102-12 External initiatives As of December 31, 2021, Equinix participated in the following initiatives, in no particular order: Accounting for Sustainability (A4S), CDP, CEO Action for Diversity & Inclusion, Clean Energy Buyers Association (CEBA), Climate Neutral Data Centre Pact, Digital Inclusion Benchmark, EcoVadis, EU Code of Conduct for Data Centres, the European Data Center Association (EUDCA), EU Data Center Operator, Global Real Estate Sustainability Benchmark (GRESB), Green Datacentre Research Programme, Information Technology Industry Council (and the former The Green Grid), ISO 14001 Environmental Management System, ISO 50001 Energy Management System, NAREIT Real Estate Sustainability Council (RESC) and ESG Forum, Paradigm for Parity, RE100, SASB, Singapore BCA-IMDA Green Mark, S&P Global Corporate Sustainability Assessment, TCFD, techUK, U .S . Environmental Protection Agency (EPA) Energy Star Data Center Rating program, U .S . EPA Green Power Partnership, U .S . Green Building Council (USGBC), VigeoEiris . Please note this list is not exhaustive . 102-13 Membership of associations Equinix’s membership in any trade association does not indicate our agreement with all views and positions taken by the association . As of December 31, 2021, we were active members of the following sample list organizations . Trade Organizations § Asia Cloud Computing Association § Data Center Coalition (DCC) § Dutch Data Centre Association § European Data Centre Association (EUDCA) § France Datacenter § German Datacenter Association § Host in Ireland § Information Technology Industry Council (ITI) § National Association of Real Estate Investment Trusts (Nareit) § Northern Virginia Technology Council (NVTC) § TechUK (United Kingdom) § US India Business Council § US Colombia Business Council GRI 102: STRATEGY Disclosure No. Disclosure Title 2021 Response 102-14 Statement from senior decision-maker CEO Letter 102-15 Key impacts, risks, and opportunities 2021 Form 10-K , Item 1A 12

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