Introduction 43 2021 Sustainability Report A Modern, High-Performing Health System Our People and Culture Environmental Health Responsible Business Practices Performance Data Optum Specialty Fusion offers a first-of-its-kind specialty medication management solution to simplify care for patients with complex conditions and lower the cost of expensive specialty drugs by allowing care providers to compare dozens of clinically appropriate, lower-cost options. Selecting a lower-cost, therapeutically equivalent immunosuppressive drug, for example, could save an average of $700 per prescription. A growing pipeline of new therapies has the potential to change medical care for individuals with rare diseases and few or no treatment options. We seek to organize and develop solutions to help patients access life-changing medications using capabilities such as outcomes-based contracting, utilization management, networks, distribution solutions and risk management. Beyond specialty medications, we are investing in solutions that provide consumers with simpler, more transparent information at the pharmacy counter. Actionable, real-time health information makes it easier for patients and their physicians to make the best possible care decisions. Transparency tools at the point of care provide patients and prescribing physicians with access to information about which drugs are covered by a patient’s health plan, how much it will cost at the pharmacy counter, or if a lower-cost alternative is available. Members benefit from better drug pricing transparency through Optum’s PreCheck MyScript tool, which delivers real-time, personalized prescription information to lower costs for consumers. Nine in 10 prescribing providers have access to PreCheck MyScript, which instantly shows providers how much a drug will cost and recommends equally effective, lower-cost alternatives, leading to better medication adherence rates for those with diabetes, high cholesterol and hypertension. MyScript Finder puts similar information into the hands of consumers through the Optum Rx mobile app, providing clinically appropriate, less expensive options with exact cost information. Members can also see different pricing options for home delivery and individual retail locations. We provide the same transparency and affordability to those without health benefits via a cash card that provides prescription drug discounts at more than 64,000 pharmacies. 17% medical and pharmacy savings through Optum Specialty Fusion. $700 average drug savings per prescription on immunosuppressive drugs. Optum Specialty Fusion impact