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21 Table 3. Proportion of patients with virological cure (negative nasopharyngeal PCR) by day, in COVID-19 patients treated with hydroxychloroquine only, in COVID-19 patients treated with hydroxychloroquine and azithomycin combination, and in COVID-19 control patients. Day3 post inclusion Day4 post inclusion Day5 post inclusion Day6 post inclusion Number of Number of Number of Number of negative negative negative negative p- p- p- patients/total % p-value patients/total % patients/total % patients/total % value value value number of number of number of number of patients patients patients patients Control patients 1/16 6.3 4/16 25.0 3/16 18.8 2/16 12.5 Hydroxychloroquine 5/14 35.7 7/14 50.0 7/14 50.0 8/14 57.1 treatment only 0.002 0.05 0.002 <0.001 Hydroxychloroquine and azithromycin 5/6 83.3 5/6 83.3 6/6 100 6/6 100 combined treatment

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