OUR PURPOSE PIONEERING SCIENCE 123 ESG DATA TABLE BIOGEN 2021 YEAR IN REVIEW PATIENTS OUR PEOPLE ENVIRONMENT COMMUNITY REPORTING Code Units 2018 2019 2020 2021 RE100 Target – Global Renewable Electricity 12 % 100 100 100 100 Fossil Fuel Free – Renewable Energy Allocation % Total energy 27 29 32 30 Water Major Facilities with Fair Share of Water Withdrawal (Target: Maintain 100%) 13 % 40 100 100 100 Water Use (ex. non-contact cooling water) Million Cubic Meters (m 3 ) 1.31 1.272 1.035 1.076 Water Use Intensity m 3 / MM USD revenue 97 88 77 83 Water Reused/Recycled 14 % 6 5 7 4 Water Withdrawal Million m 3 1.629 1.511 1.265 1.368 • Municipal Supply (potable & grey water) Million m 3 0.895 0.758 0.590 0.581 • Fresh Surface Water (non-contact cooling) Million m 3 0.411 0.303 0.303 0.333 • Groundwater Million m 3 0.322 0.447 0.370 0.453 • Rainwater Million m 3 0.001 0.001 0.001 0.001 Water Discharges Million m 3 1.214 0.99 0.806 0.825 • Fresh Surface Water Million m 3 0.4 0.303 0.303 0.333 • Wastewater Million m 3 0.815 0.687 0.503 0.492 Waste 15 Non-hazardous Waste 16 MT 8,161 7,561 2,841 3,510 Reused MT 11 6 39 76 Recycled MT 932.4 1,732 527 497.8 Composted MT 3,334 2,997 909 200 Energy Recovery via Anaerobic Digestion MT 70 43 0 0 Waste to Energy 17 MT 1,309 1,206 879 1,361 Incineration 18 MT 2,472 1,544 455 1,367 Landfill MT 33 32 32 6 Non-hazardous Waste Intensity MT / MM USD Revenue 0.61 0.53 0.21 0.32 Waste to Landfill Diversion (Target: Maintain 100%) % 100 100 99 100 Recovery & Recycling Rate (Non-hazardous Waste) % 53 63 52 22