OUR PURPOSE PIONEERING SCIENCE 146 GRI CONTENT INDEX BIOGEN 2021 YEAR IN REVIEW PATIENTS OUR PEOPLE ENVIRONMENT COMMUNITY REPORTING GRI indicator Reporting Requirements 2021 Response Alignment SDG 307 Environmental Compliance 307–1 a. Significant fines and non-monetary sanctions for non-compliance with environmental laws and/or regulations in terms of: • Total monetary value of significant fines. • Total number of non-monetary sanctions. • Cases brought through dispute resolution mechanisms. b. If the organization has not identified any non-compliance with environmental laws and/or regulations, a brief statement of this fact is sufficient. There were no significant instances of non-compliance in 2021. Principles, Policies & Positions Item 1A., Risk Factors, 2021 Annual Report 308 Supplier Environmental Assessment 308–1 Percentage of new suppliers that were screened using environmental criteria. Responsible Supply Chain update Environment – 2021 Year in Review 308–2 Negative environmental impacts in the supply chain and actions taken a. Number of suppliers assessed for environmental impacts. b. Number of suppliers identified as having significant actual and potential negative environmental impacts. c. Significant actual and potential negative environmental impacts identified in the supply chain. d. Percentage of suppliers identified as having significant actual and potential negative environmental impacts with which improvements were agreed upon as a result of assessment. e. Percentage of suppliers identified as having significant actual and potential negative environmental impacts with which relationships were terminated as a result of assessment, and why. Responsible Supply Chain update Item 1A., Risk Factors, 2021 Annual Report Environment – 2021 Year in Review Reporting – 2021 Year in Review GRI 400 SOCIAL 401 Employment 401–1 a. Total number and rate of new employee hires during the reporting period, by age group, gender and region. b. Total number and rate of employee turnover during the reporting period, by age group, gender and region. Our People – 2021 Year in Review ESG Data Table – 2021 Year in Review SASB Content Index – 2021 Year in Review * 403 Occupational Health and Safety 403–1 a. A statement of whether an occupational health and safety management system has been implemented, including whether: • The system has been implemented because of legal requirements and, if so, a list of the requirements. • The system has been implemented based on recognized risk management and/or management system standards/guidelines and, if so, a list of the standards/guidelines. b. A description of the scope of workers, activities and workplaces covered by the occupational health and safety management system, and an explanation of whether and, if so, why any workers, activities or workplaces are not covered. Corporate Responsability Environmental, Health and Safety Policy Statement Our People – 2021 Year in Review