$2.2 Billion Market Opportunity1 • 744 MM Current Annual Usage in Target Markets (SAM) Current usage in our targeted dental markets—North America, Western Europe, 1 Japan, and South Korea—is 744 million units. TAM worldwide is 1.9 billion units . • $220 MM Est. Revenue for Each 10% of Market Share BPI has a target average wholesale price of $3.00 per cartridge in our targeted dental markets. • Additional Medical Market Potential 2 BPI’s patent-pending medical vial technology may allow entry into dermatology, plastic surgery, emergency medicine, interventional radiology, and podiatry markets. 1 SDM Northcoast report, “Injectable Carpules Market Size Analysis, United States, Canada, Mexico, 2019 Units”, July 15, 2021; Key-stone Research, “European Local Anesthetics Market Survey,” September 20, 2021; Balanced Pharma Internal Estimates; https://www.dentistrytoday.com/dental-pain- control-and-local-anesthesia-a-40-year-journey/ ; 2BPI owns the following granted patents and pending patent applications: U.S. Patent No. 11,305,064 (issued April 19th, 2022); U.S. Application No. 17/722,016; International PCT Application No. PCT/IB2018/052598; Canadian Application No. 3,111,347 (Canadian National Phase of PCT/IB2018/052598); European Application No. 18897951.2 (European Regional Phase of PCT/IB2018/052598); Japanese Application No. 2020-556351 (Japanese National Phase of PCT/IB2018/052598); Korean Application No. 10-2020-7021685 (Republic of Korea National Phase of PCT/IB2018/052598); U.S. Application No. 16/655,362; U.S. Application No. 63/233,879; BPI also owns one trademark application, U.S. Application No. 88/198,808, pending for the LIBRACAINE mark. PRIVATE & CONFIDENTIAL