“This report represents the efforts of our team — 76,000 employees of all walks of life and backgrounds — and the countless moments of impact we’ve collectively shared over the past year.” A message from our Chief Executive Officer We continue to live in an era of exponential advancement in healthcare — yet the global events of fiscal year 2021 (FY21) reinforced the need to reach beyond our industry and help make the world we live in more sustainable and equitable. Now, more than ever, McKesson is focused on enabling lasting change as an impact-driven organization. We understand the most pressing issues of our time cannot be solved without strong leadership, and we believe we are positioned to make measurable and enduring positive impacts for our employees, partners, communities and customers, our customers' patients and their families, and the planet. As part of this focus, in FY21, we welcomed Kelvin A. Baggett, M.D. to serve as our Chief Impact Officer and a member of our executive operating team. Under Kelvin’s leadership, we created our first- ever Global Impact Organization (GIO), bringing together diversity, equity and inclusion; community investment and the McKesson Foundation; and sustainability and environment, social and governance (ESG) under a single business function to amplify our collective efforts. To further center our daily actions around driving positive change, we view our global impact work as a core element of our enterprise strategy. Part of this effort was the development of a new purpose statement, Advancing Health Outcomes for All ™ , which articulates how we believe McKesson can use its expertise to make the most meaningful impact. In addition, in fiscal year 2022 (FY22), we expanded the “I” in our I 2 CARE values to represent inclusion — in addition to integrity — as a symbol of our commitment to a work environment that embraces and respects what makes each of us unique. This report represents the efforts of our team — 76,000 employees of all walks of life and backgrounds — and the countless moments of impact we’ve collectively shared over the past year. With our eyes on the future, this report also sets a bold vision for how McKesson will lead in the years to come as an impact-driven organization, fueled by people who use their unique talents and skills to be responsible global citizens and help achieve our purpose. I am proud of the work Team McKesson has done and continues to do to galvanize the positive impact we can have in responding to the critical needs of our society and our planet. And, working in partnership with others, I believe we can build a brighter future that offers greater health outcomes for all. Sincerely, Brian Tyler Chief Executive Officer, McKesson Corporation Introduction Stories Employees Access Equity Climate Operations >Table of Contents | 3 FY21 Impact Report