“For us, ‘Advancing Health Outcomes for All’ is more than a tagline; it’s our recognition that together, we can measurably improve human health.” A message from our Chief Impact Officer When I joined McKesson in November 2020, I was immediately impressed with our genuine commitment to making a meaningful difference in the lives of others. That included taking deliberate actions to address social and environmental issues. Some of those issues, while not new, were made more apparent and extreme by the COVID-19 pandemic. For McKesson, this is not the first time in our 188-year history that the world has experienced a global pandemic, social unrest, or an economic crisis. Nevertheless, those events are jarring and unsettling, and can reveal the true values and character of a company. Ignoring them will not make them disappear or any less consequential. And, while hindsight gives us the opportunity to reflect on what we did, we must remind ourselves of, and take satisfaction in, the decisions we made in the moment. As it did for many of us individually, the pandemic prompted internal reflection for McKesson. An output of that process and ensuing conversations led us to undertake a discovery process to capture our purpose in words. The intent was to examine what drives Team McKesson and what will continue to guide and inform our future actions. That work led us to define what is now our unifying purpose: Advancing Health Outcomes for All. For us, it’s more than a tagline; it’s our recognition that together, we can measurably improve human health. While the report that follows does not cover every program and initiative from FY21, it is intended to provide an update on the progress we’ve made toward living our purpose. We are a dynamic and ever-evolving company. We recognize that for our current and future success, diversity matters. Therefore, we are committed to attracting, developing and retaining a talented and diverse workforce. We recognize extreme weather events are happening at a greater frequency and scale due to human influence on the planet, and we strive to reduce our negative environmental impacts. We know that while we would like to contribute to many causes, focusing our charitable efforts gives us the best chance to make a meaningful difference. Underpinning our success and ability to address and invest in initiatives supporting our purpose is the structure and integrity of our robust approach to corporate governance and responsible operations. Employees drive the momentum behind this approach, enabling us to be a business leader in our communities and by embracing and displaying our I 2 CARE and ILEAD values. Introduction Stories Employees Access Equity Climate Operations >Table of Contents | 4 FY21 Impact Report

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