In FY21, we developed an initial framework, Care 360° TM , which serves as the lens for our efforts to promote a more equitable and resilient society by leveraging McKesson’s inherent expertise and resources. This 360-degree approach centers around three initial areas of focus — improving Access to Care, advancing Health Equity and delivering Climate Action for Health in service to our employees, customers, patients and their families, partners, communities, and the planet. Guided by this strategy, in FY22, we set our first public ESG-related commitments, which included a representation goal for our workforce and a pledge to set science-based targets. We also made a public statement on climate change. We look forward to sharing more about our progress and the evolution of this framework in next year’s Impact Report. It is our hope that this report demonstrates to our stakeholders that we will leverage our capabilities to address relevant and important business and societal issues. We strive to make care more affordable and accessible, to create opportunities for people to fulfill their innate potential, and to conduct ourselves in ways that promote the overall health of our planet. I am energized and confident that together we can and will make an impact and create a brighter future for all. Sincerely, Kelvin A. Baggett, M.D. Chief Impact Officer, McKesson Corporation Introduction Stories Employees Access Equity Climate Operations >Table of Contents | 5 FY21 Impact Report >Table of Contents | 5