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2021–2022 SASB INDEX American Express Sustainability Accounting Standards Board (SASB) Index This Index reflects our report in accordance with Industry Standards Version 2018–10 issued by the Sustainability Accounting Standards Board (SASB). Our disclosures under those standards are based on three SICS industries that are most closely aligned with our mix of businesses: Consumer Finance (FN-CF), Commercial Banks (FN-CB), and Software and IT Services (TC-SI). Unless otherwise noted, all data and descriptions are reported for the American Express Company on a consolidated basis where applicable and not just the businesses or segments relevant to a particular industry. We do not currently disclose all metrics included in the standards for these three SICS industries but will continue to evaluate them in the future. Our commitment is to provide investors with useful, relevant, and meaningful sustainability information and we may evolve our disclosures on these SASB topics over time. All reported data is as of and for the year ended December 31, 2021, unless otherwise noted. While most information is found in our 2021–2022 ESG Report, other primary sources include our 2021 Annual Report on Form 10-K , 2022 Proxy Statement , 2021 CDP Climate Change Response , and American Express website . SASB Topic Accounting Metric Code Response Business Ethics Total amount of monetary losses as a result of legal proceedings associated with fraud, insider trading, anti-trust, anti-competitive behavior, market manipulation, malpractice, or other related financial industry laws or regulations FN-CB-510a.1 F Form 10-K on page 127: Note 12: Contingencies and Commitments Description of whistleblower policies and procedures FN-CB-510a.2 ESG Report: Our Business Ethics pages 82-83, American Express AEMP17–Whistleblower Claims Policy Customer Privacy Number of account holders whose information is used for secondary purposes FN-CF-220a.1 TC-SI-220a.2 American Express does not report a metric on the bases specified in the standard. American Express’ online Privacy Center and its Privacy Statement describe the information we collect from our customers and how we use it. Total amount of monetary losses as a result of legal proceedings associated with customer privacy FN-CF-220a.2 TC-SI-220a.3 American Express discloses all material legal proceedings in our SEC reports. INTRODUCTION PROMOTING DE&I ADVANCING CLIMATE SOLUTIONS BUILDING FINANCIAL CONFIDENCE OUR ESG GOVERNANCE & OPERATING RESPONSIBLY SUPPORTING DATA OUR COMMITMENT TO ESG 110

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