80 SUSTAINABILITY PRODUCT FORMULATION SAFETY REVIEW PROCESS When we first begin to consider using an ingredient, we evaluate it to be sure that it meets our safety standards and the requirements of governmental, regulatory, and scientific bodies around the world. We then study all aspects of the ingredient. If needed, experiments are conducted in state-of-the-art in vitro tests and/or computer-based models to further inform our understanding of the ingredient’s safety profile. This ingredient information guides us as we formulate our products. We then evaluate the formula itself to assure the safety of the full formula, while comparing it to similar formulas within our extensive database of clinical and safety data. Additional clinical and in vitro testing may also be conducted among volunteer panels to further confirm safety. Once the cosmetic formula meets our safety and quality standards, it is placed on the market for our consumers to enjoy. We continuously monitor feedback from our consumers, allowing us to understand the impact of our products as they are being used. PRODUCT SAFETY PHILOSOPHY AND PROCESS We evaluate each product for safety. We employ a sophisticated evaluation plan that incorporates a selection of relevant tools, including, for example, a suite of tests such as stability, sensory, safety-in-use, and clinical tests, as well as ophthalmologist and dermatologist testing. Our integrated global R&D network constantly works to advance modern, scientific cosmetic testing methodologies. ANIMAL TESTING We have worked globally to establish that product safety for cosmetics can be determined via nonanimal, modern, and scientific evaluation and methods—leveraging deep knowledge of toxicology, skin biology, historical and current data, and evaluations of cosmetic ingredients, while utilizing the most up-to-date scientific methodologies, in silico, in vitro, and clinical. More than 25 years ago, we began using synthetic skin technology to evaluate the effects of products on human skin and have been updating our methodologies ever since. The Estée Lauder Companies was one of the first cosmetics companies to eliminate animal testing as a method of determining product safety. We don’t test our products on animals, and we don’t ask others to test for us. We acknowledge our brands are sold in countries where animal testing of cosmetics or cosmetic ingredients is required by law. We believe it is our responsibility to contribute to the sustainable solution to end animal testing for cosmetics and are proud to work with organizations advocating for practical solutions and acceptance of alternatives to cosmetic animal testing. We invest in university research programs, industry consortiums, and nonprofits that champion a collaborative and effective approach. For more information on our Animal Testing policies, please visit our website. We seek to advance best practices within the industry and enhance our collective knowledge of cosmetics and cosmetics ingredients. • We are members of the Personal Care Products Council, which supports the work of the Cosmetic Ingredient Review. • We also support the International Cooperation on Cosmetics Regulation.