Code GRI Disclosure Reference/Location 2-11 Chair of the highest governance body Stephen J. Squeri CEO & Chairman— 2022 Proxy Statement on page 12 2-12 Role of the highest governance body in overseeing the management of impacts 2021–2022 ESG Report: ESG Governance on pages 76-88, 2022 Proxy Statement on page 24 2-13 Delegation of responsibility for management of impacts 2021–2022 ESG Report: ESG Governance on pages 76-88 2-14 Role of the highest governance body in sustainability reporting 2021–2022 ESG Report: ESG Governance on pages 76-88 2-15 Conflicts of interest 2022 Proxy Statement on pages 16-27 and 33 2-16 Communications of critical concerns 2021–2022 ESG Report: Our Business Ethics on pages 82-83, Code of Conduct , Amex Ethics Hotline 2-17 Collective knowledge of the highest governance body 2022 Proxy Statement on pages 7-13 2-18 Evaluation of the performance of the highest governance body 2022 Proxy Statement on pages 16-17 2-19 Renumeration policies 2021–2022 ESG Report: ESG and Executive Compensation on page 81, 2022 Proxy Statement on pages 47-77 2-20 Process to determine renumeration 2022 Proxy Statement on pages 48–55 2-21 Annual total compensation ratio 2022 Proxy Statement on page 77 2-22 Statement on sustainable development strategy 2021–2022 ESG Report: A Message from Our Chairman and CEO on pages 4-7 2-23 Policy commitments 2021–2022 ESG Report: Our Business Ethics on pages 82-83, Supporting Data: Key Policies on page 101, Corporate Governance Principles , Code of Conduct , Human Rights Statement , American Express Policy Engagement and Political Activity 2-24 Embedding policy commitments 2021–2022 ESG Report: Our Business Ethics on pages 82-83 2-25 Processes to remediate negative impacts 2021–2022 ESG Report: Our Business Ethics on pages 82-83, Code of Conduct 2-26 Mechanisms for seeking advice and raising concerns 2021–2022 ESG Report: Our Business Ethics on pages 82-83, Code of Conduct , Amex Ethics Hotline 2-27 Compliance with laws and regulations Form 10-K Note 12 : Contingencies and Commitments on pages 127-129 2-28 Membership associations 2021–2022 ESG Report: Supporting Data: ESG Partnerships on page 92 2-29 Approach to stakeholder engagement 2021–2022 ESG Report: Supporting Data: Our Commitment to ESG on pages 90-92 2-30 Collective bargaining agreements We have a small number of employees which were subject to collective bargaining agreements in 2021. We believe that relations with our employees are positive. GRI 3: Material Topics (2021) 3-1 Process to determine material topics 2021–2022 ESG Report: Supporting Data: Our Priority ESG Issues on page 90 3-2 List of material topics 2021–2022 ESG Report: Supporting Data: ESG Priority Issues Matrix on page 90 3-3 Management of material topics 2021–2022 ESG Report INTRODUCTION PROMOTING DE&I ADVANCING CLIMATE SOLUTIONS BUILDING FINANCIAL CONFIDENCE OUR ESG GOVERNANCE & OPERATING RESPONSIBLY SUPPORTING DATA OUR COMMITMENT TO ESG 115