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Table of contents A letter from our Chairman, CEO, and President Steve Rusckowski ..................................... 3 A conversation with CEO-elect Jim Davis ................................................................................. 4 2021 overview Company overview ...................................................................................................................... 6 2021 highlights ............................................................................................................................ 7 Approach to corporate responsibility through our ESG strategy ........................................... 8 Materiality assessment .............................................................................................................. 9 Stakeholder engagement ........................................................................................................ 10 Governance ............................................................................................................................... 11 Board of Directors oversight on corporate responsibility and ESG .................................... 12 Awards and honors .................................................................................................................. 13 COVID-19: Challenges, accomplishments, and opportunities Highlights of our COVID-19 response .................................................................................... 15 Working with the CDC and others to advance understanding of SARS-CoV-2 .................. 16 Bringing COVID-19 testing to New York’s first responders .................................................. 17 Transitioning to life with COVID-19: a new normal ............................................................... 18 Multiple testing options to get—and keep—employees working safely ........................... 19 Nationwide COVID-19 testing initiatives to support safer classrooms ............................. 20 Quest’s initiatives for returning to the “business of play” .................................................... 21 Promoting a healthier world Thought leadership marries insights to influence ............................................................... 24 Key insights on current and emerging healthcare issues ................................................... 25 Improving outcomes for the leading cause of death in the US ........................................... 28 Disparities in breast cancer mortality and treatment ......................................................... 29 Expanding the possibilities with Quest Advanced Neurology ............................................. 30 Advancing healthcare equity in underserved communities ............................................... 31 Keeping kids and families healthy and active ...................................................................... 32 Eliminating disparities in healthcare leadership ................................................................. 33 Addressing COVID-19 in Black communities: Choose Healthy Life .................................... 34 Quest for Health Equity aims to improve healthcare access .............................................. 35 Quest HealthConnect: personalized access to quality healthcare .................................... 36 Increasing access to preventive care through QuestDirect ................................................. 37 Creating an inspiring workplace Our culture rests on equity in compensation and opportunity ........................................... 39 Creating opportunities for excellence .................................................................................... 40 Workforce demographics ........................................................................................................ 41 Benefits that support wellness and prevention ................................................................... 43 Safely working together ........................................................................................................... 44 New tests yield actionable insights ....................................................................................... 45 Bringing our whole selves to work .......................................................................................... 46 Our I&D learning journey ......................................................................................................... 47 Inclusion and Diversity Council inspires new and ongoing initiatives ................................ 48 Inclusion in action: Clifton and West Hills labs ..................................................................... 49 Employee Business Networks reflect and drive Quest values ............................................ 50 Our holistic approach to learning and development ............................................................ 51 Investing in our people ............................................................................................................. 52 Employees are sharing, and we’re listening .......................................................................... 53 Supporting and recognizing all Quest employees ................................................................ 54 RecognitionQuest: a culture of appreciation, celebration, and rewards ............................ 55 Major accolades awarded to our colleagues ........................................................................ 56 Building value State-of-the-art lab opens in Clifton, NJ .............................................................................. 58 Quest collaborations on the cutting edge ............................................................................. 60 Wherever we are, Quest is part of the community ................................................................ 61 Memberships, sponsorships, and affiliations ...................................................................... 63 Environmental sustainability drives operational excellence .............................................. 64 Integrity: a fundamental value ................................................................................................ 67 Cybersecurity and data privacy are high-level priorities ..................................................... 69 Driving supplier excellence and innovation through collaboration .................................... 71 References SASB Sustainability Accounting Standards Index ............................................................... 73 About this report ...................................................................................................................... 78 References ................................................................................................................................ 79 Quest, Quest Diagnostics, any associated logos, and all associated Quest Diagnostics registered or unregistered trademarks are the property of Quest Diagnostics. All third-party marks— ® and ™—are the property of their respective owners. ® 2022 Quest Diagnostics Incorporated. All rights reserved. MI10666 7/2022

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